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Excerpt from techxplore.com
The transition from traditional 2D to 3D microfluidic structures is a significant advancement in microfluidics, offering benefits in scientific and industrial applications. These 3D systems improve throughput through parallel operation, and soft elastomeric networks, when filled with conductive materials like liquid metal, allowing for the integration of microfluidics and electronics.
However, traditional methods such as soft lithography fabrication which requires cleanroom facilities have limitations in achieving fully automated 3D interconnected microchannels. The manual procedures involved in these methods, including polydimethylsiloxane (PDMS) molding and layer-to-layer alignment, hinder the automation potential of microfluidic device production.
3D printing is a promising alternative to traditional microfluidic fabrication methods. Photopolymerization techniques like stereolithography apparatus (SLA) and digital light processing (DLP) enable the creation of complex microchannels.
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